Steroid vs. Platelet-Rich Plasma in Ultrasound-Guided Sacroiliac Joint Injection for Chronic Low Back Pain.

نویسندگان

  • Varun Singla
  • Yatindra K Batra
  • Neerja Bharti
  • Vijay G Goni
  • Neelam Marwaha
چکیده

BACKGROUND Despite widespread use of steroids to treat sacroiliac joint (SIJ) pain, their duration of pain reduction is short. Platelet-rich plasma (PRP) can potentially enhance tissue healing and may have a longer-lasting effect on pain. OBJECTIVES To assess the efficacy and safety of PRP compared with methylprednisolone in ultrasound-guided SIJ injection for low back pain. STUDY DESIGN Prospective randomized open blinded end point (PROBE) study. METHODS Forty patients with chronic low back pain diagnosed with SIJ pathology were randomly allocated into 2 groups. Group S received 1.5 mL of methylprednisolone (40 mg/mL) and 1.5 mL of 2% lidocaine with 0.5 mL of saline, while Group P received 3 mL of leukocyte-free PRP with 0.5 mL of calcium chloride into ultrasound-guided SIJ injection. Visual analog scale (VAS) scores, Modified Oswestry Disability Questionnaire (MODQ) scores, Short Form (SF-12) Health Survey scores, and complications (if any) were evaluated at 2 weeks, 4 weeks, 6 weeks, and 3 months. RESULTS Intensity of pain was significantly lower in Group P at 6 weeks (median [interquartile range (IQR)] = 1 [1 to 1] vs. 3.5 [2 to 5]; P = 0.0004) and 3 months (Median [IQR] = 1 [1 to 3] vs. 5 [3 to 5]; P = 0.0002) as compared to Group S. The efficacy of steroid injection was reduced to only 25% at 3 months in Group S, while it was 90% in Group P. A strong association was observed in patients receiving PRP and showing a reduction of VAS ≥ 50% from baseline when other factors were controlled. The MODQ and SF-12 scores were improved initially for up to 4 weeks but deteriorated further at 3 months in Group S, while both the scores improved gradually for up to 3 months in Group P. CONCLUSION The intra-articular PRP injection is an effective treatment modality in low back pain involving SIJ.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ultrasound-guided sacroiliac joint injection technique.

We describe a case report and technique for using a portable ultrasound scanner and a curvilinear transducer (4-5MHz) (SonoSite Micromaxx SonoSite, Inc. 21919 30th Drive SE Bothwell W. A.) to guide sacroiliac joint (SIJ) injection. A 42-year-old male presented with chronic lower back pain centered on his left SIJ. His pain averaged 7 out of 10 (numerical rating scale). For the ultrasound-guided...

متن کامل

A comparison of ultrasound guided corticosteroid injection vs ozone injection in grade 3 knee osteoarthritis

Background: Osteoarthritis (OA) is a degenerative disease that can cause pain and limited function. One of the non-surgical treatments is intra-articular ozone injection. This study aimed to compare the effect of ultrasound-guided corticosteroid injection with ozone injection in patients with grade 3 osteoarthritis of the knee. Methods: This randomized, double-blind, clinical trial was carried...

متن کامل

Ultrasound Guided Dextrose Prolotherapy and Platelet Rich Plasma Therapy in Chronic Low Back Pain: Three Case Reports

For patients with osteoarthritis (OA) involving the spine, proper diagnosis, pain management and functional outcomes remain poor and inconsistent. This is despite widely used therapies such as steroid and Botulinum toxin injections, chemonucleolysis, radiofrequency denervation, intradiscal electrothermal therapy, pain management pumps, spinal cord stimulators, and surgery [1,2]. Most of these o...

متن کامل

An Exploration of Ultrasound-Guided Therapeutic Injection of the Dorsal Interosseous Ligaments of the Sacroiliac Joint for Mechanical Dysfunction of the Joint

Mechanical dysfunction of the sacroiliac joint is a common cause of lateralising low back pain in young patients in either the peri-partum period or after trauma. Diagnosis is based on evidence-based clinical guidelines and fused scintigraphic tomographic and x-ray computed tomography studies (SPECT/ CT). Accurate diagnosis is important as up to 80% of these patients respond to directed physiot...

متن کامل

Comment on: Ultrasound-guided sacroiliac joint injection in patients with established sacroiliitis: precise IA injection verified by MRI scanning does not predict clinical outcome.

OBJECTIVE IA injections of SIJs with corticosteroids are often performed in patients suffering from low back pain due to active sacroiliitis. However, SIJ injections are technically demanding, and therefore the clinical outcome of ultrasound-guided corticosteroid SIJ injections was analysed in relation to the accuracy of the injection. METHODS Ultrasound-guided injections were performed with ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Pain practice : the official journal of World Institute of Pain

دوره 17 6  شماره 

صفحات  -

تاریخ انتشار 2017